Research

[Lancet] A familial cluster of COVID-19 pneumonia: Study of a family cluster

The Lancet, 24 January 2020

Jasper Fuk-Woo Chan, Shuofeng Yuan, Kin-Hang Kok, Kelvin Kai-Wang To, Hin Chu, Jin Yang, Fanfan Xing, Jieling Liu, Cyril Chik-Yan Yip, Rosana Wing-Shan Poon, Hoi-Wah Tsoi, Simon Kam-Fai Lo, Kwok-Hung Chan, Vincent Kwok-Man Poon, Wan-Mui Chan, Jonathan Da Bu niel Ip, Jian-Piao Cai, Vincent Chi-Chung Cheng, Honglin Chen, Christopher Kim-Ming Hui, Kwok-Yung Yuen

Chronology of symptom onset of the Shenzhen family cluster and their contacts in Wuhan

Highlights

  • No data on the person-to-person or nosocomial transmission of the novel coronavirus has been published to date.
  • The epidemiological, clinical, laboratory, radiological and microbiological findings from five patients in a family cluster who presented with unexplained pneumonia after a visit to Wuhan, and an additional family member who did not travel to Wuhan.
  • A family of six patients who travelled to Wuhan from Shenzhen between 29 Dec 2019 and 4 Jan 2020 was enrolled. Of the six family members who travelled to Wuhan, five were identified as infected with the novel coronavirus. Additionally, one family member, who did not travel to Wuhan, became infected with the virus after several days of contact with four of the family members.
  • Findings are consistent with person-to-person transmission of this novel coronavirus in hospital and family settings, and the reports of infected travellers in other geographical regions.

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