Jasper Fuk-Woo Chan
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In the News
HKU researchers find Covid-19 treatment with ulcer drug
A HKU study has discovered that an existing drug commonly used for stomach ulcers could be effective for treating the…
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Research
[Nature Microbiology] Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters
Nature Microbiology, 7 October 2020 Shuofeng Yuan, Runming Wang, Jasper Fuk-Woo Chan, Anna Jinxia Zhang, Tianfan Cheng, Kenn Ka-Heng Chik,…
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Research
[Cell Reports Medicine] Oral SARS-CoV-2 inoculation establishes subclinical respiratory infection with virus shedding in golden Syrian hamsters
Cell Reports Medicine, 21 September 2020 Andrew Chak-Yiu Lee, Anna Jinxia Zhang, Jasper Fuk-Woo Chan, Can Li, Zhimeng Fan, Feifei…
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Research
[Infection] Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms
Infection, 17 September 2020 Li, X., Chan, J.F., Li, K.K. et al. Highlights: A total of 158 conjunctival swabs were…
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Research
[Science Advances] Viruses harness YxxØ motif to interact with host AP2M1 for replication: a vulnerable broad-spectrum antiviral target
Science Advances, 14 August 2020 Yuan, S.F., Chu, H., Huang, J.J. & et al. Highlights: Discovered a common YxxØ-motif of…
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Research
[Cell Research] SARS-CoV-2 infects human neural progenitor cells and brain organoids
Cell Research, 4 August 2020 Bao-Zhong Zhang, Hin Chu, Shuo Han, Huiping Shuai, Jian Deng, Ye-fan Hu, Hua-rui Gong, Andrew…
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Research
[Nature] Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
Nature, 24 July 2020 Riva, L., Yuan, S., Yin, X. et al. Highlights: Profiled a library of known drugs encompassing…
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Research
[Journal of Clinical Virology] Evaluation of simple nucleic acid extraction methods for the detection of SARS-CoV-2 in nasopharyngeal and saliva specimens during global shortage of extraction kits
Journal of Clinical Virology, 23 June 2020 Allen Wing-Ho Chu, Wan-Mui Chan, Jonathan Daniel Ip, Cyril Chik-Yan Yip, Jasper Fuk-Woo…
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Research
[The Journal of Infectious Diseases] Attenuated interferon and pro-inflammatory response in SARS-CoV-2-infected human dendritic cells is associated with viral antagonism of STAT1 phosphorylation
The Journal of Infectious Diseases, 21 June 2020 Dong Yang, Hin Chu, Yuxin Hou, Yue Chai, Huiping Shuai, Andrew Chak-Yiu…
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