Shuofeng Yuan
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Research
Co-infection by severe acute respiratory syndrome coronavirus 2 and influenza virus enhances the severity of pneumonia in golden Syrian hamsters
Clinical Infectious Diseases, 20 December 2020 Anna Jinxia Zhang, Andrew Chak-Yiu Lee, Jasper Fuk-Woo Chan, Feifei Liu, Can Li, Yanxia…
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Research
![Photo of [Nature Microbiology] Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters](https://fightcovid19.hku.hk/content/uploads/2020/10/Image-2-390x220.jpg)
[Nature Microbiology] Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters
Nature Microbiology, 7 October 2020 Shuofeng Yuan, Runming Wang, Jasper Fuk-Woo Chan, Anna Jinxia Zhang, Tianfan Cheng, Kenn Ka-Heng Chik,…
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Research
![Photo of [Cell Reports Medicine] Oral SARS-CoV-2 inoculation establishes subclinical respiratory infection with virus shedding in golden Syrian hamsters](https://fightcovid19.hku.hk/content/uploads/2020/10/fx1_lrg-e1601870075235-390x220.jpg)
[Cell Reports Medicine] Oral SARS-CoV-2 inoculation establishes subclinical respiratory infection with virus shedding in golden Syrian hamsters
Cell Reports Medicine, 21 September 2020 Andrew Chak-Yiu Lee, Anna Jinxia Zhang, Jasper Fuk-Woo Chan, Can Li, Zhimeng Fan, Feifei…
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Research
![Photo of [Science Advances] Viruses harness YxxØ motif to interact with host AP2M1 for replication: a vulnerable broad-spectrum antiviral target](https://fightcovid19.hku.hk/content/uploads/2020/05/fusion-medical-animation-EAgGqOiDDMg-unsplash-1-390x220.jpg)
[Science Advances] Viruses harness YxxØ motif to interact with host AP2M1 for replication: a vulnerable broad-spectrum antiviral target
Science Advances, 14 August 2020 Yuan, S.F., Chu, H., Huang, J.J. & et al. Highlights: Discovered a common YxxØ-motif of…
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Research
[The Journal of Infectious Diseases] Attenuated interferon and pro-inflammatory response in SARS-CoV-2-infected human dendritic cells is associated with viral antagonism of STAT1 phosphorylation
The Journal of Infectious Diseases, 21 June 2020 Dong Yang, Hin Chu, Yuxin Hou, Yue Chai, Huiping Shuai, Andrew Chak-Yiu…
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Research
![Photo of [Clinical Infectious Diseases] Surgical mask partition reduces the risk of non-contact transmission in a golden Syrian hamster model for Coronavirus Disease 2019 (COVID-19)](https://fightcovid19.hku.hk/content/uploads/2020/05/Screenshot-2020-05-18-at-7.07.38-PM-390x220.png)
[Clinical Infectious Diseases] Surgical mask partition reduces the risk of non-contact transmission in a golden Syrian hamster model for Coronavirus Disease 2019 (COVID-19)
Clinical Infectious Diseases, 30 May 2020 Jasper Fuk-Woo Chan, Shuofeng Yuan, Anna Jinxia Zhang, Vincent Kwok-Man Poon, Chris Chung-Sing Chan,…
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Research
A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals
Laura Riva, Shuofeng Yuan, Xin Yin, Laura Martin-Sancho, Naoko Matsunaga, Sebastian Burgstaller-Muehlbacher, Lars Pache, Paul P. De Jesus, Mitchell V. Hull, Max Chang, Jasper Fuk-Woo Chan, Jianli Cao, Vincent Kwok-Man Poon, Kristina Herbert, Tu-Trinh Nguyen, Yuan Pu, Courtney Nguyen, Andrey Rubanov, Luis Martinez-Sobrido, Wen-Chun Liu, Lisa Miorin, Kris M. White, Jeffrey R. Johnson, Christopher Benner, Ren Sun, Peter G. Schultz, Andrew Su, Adolfo Garcia-Sastre, Arnab K. Chatterjee, Kwok-Yung Yuen, Sumit K. Chanda Highlights: Sumit Chanda’s lab in the Immunity and…
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Research
![Photo of [The Lancet Microbe] Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study](https://fightcovid19.hku.hk/content/uploads/2020/05/fusion-medical-animation-EAgGqOiDDMg-unsplash-390x220.jpg)
[The Lancet Microbe] Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study
The Lancet Microbe, 21 April 2020 Hin Chu, Jasper Fuk-Woo Chan, Terrence Tsz-Tai Yuen, Huiping Shuai, Shuofeng Yuan, Yixin Wang,…
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Research
![Photo of [Clinical Infectious Diseases] Simulation of the clinical and pathological manifestations of COVID-19 in golden Syrian hamster model: implications for disease pathogenesis and transmissibility](https://fightcovid19.hku.hk/content/uploads/2020/04/Webp.net-resizeimage-390x220.png)
[Clinical Infectious Diseases] Simulation of the clinical and pathological manifestations of COVID-19 in golden Syrian hamster model: implications for disease pathogenesis and transmissibility
Clinical Infectious Diseases, 26 Mar 2020 Jasper Fuk-Woo Chan, Anna Jinxia Zhang, Shuofeng Yuan, Vincent Kwok-Man Poon, Chris Chung-Sing Chan,…
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Research
![Photo of [Emerging Microbes & Infections] Genomic characterization of COVID-19 isolated from a patient who visited Wuhan](https://fightcovid19.hku.hk/content/uploads/2020/01/TEMI_A_1719902_F0001_OC-e1585203563614-390x220.jpg)
[Emerging Microbes & Infections] Genomic characterization of COVID-19 isolated from a patient who visited Wuhan
Emerging Microbes & Infections, 28 Jan 2020 Jasper Fuk-Woo Chan, Kin-Hang Kok, Zheng Zhu, Hin Chu, Kelvin Kai-Wang To, Shuofeng…
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